High-resolution NMR: Solid-state NMR.

High-resolution NMR in the native state

High-resolution NMR provides increasing possibilities to probe biomolecular structure in the native state. In this issue, Luchinat and Banci [IUCrJ (2017), 4, 108-118] discuss progress on using in-cell NMR in prokaryotic and eukaryotic cell preparations.

Solid-State NMR Spectroscopy

A number of arylamides have been synthesized and found to exhibit potent antimicrobial activities against a broad spectrum of Gram-positive and Gram-negative bacteria while exhibiting low toxicity toward eukaryotic cells. These facially amphiphilic foldamers have a relatively rigid intramolecular hydrogen-bonded arylamide as a framework, which places trifluormethyl versus positively charged ami...

Atomic-resolution structure of cytoskeletal bactofilin by solid-state NMR*

Bactofilins are a recently discovered class of cytoskeletal proteins of which no atomic-resolution structure has been reported thus far. The bacterial cytoskeleton plays an essential role in a wide range of processes, including morphogenesis, cell division, and motility. Among the cytoskeletal proteins, the bactofilins are bacteria-specific and do not have a eukaryotic counterpart. The bactofil...

ucture using solid-state NMR

An overview of solid-state NMR structural studies on various silk forms and analogs conducted by the authors' research groups is presented. The well-studied silkworm and spider silks together with related silk peptides have a mixture of secondary structures including b-sheet, b-turn, helix and random coil that are difficult to analyze by X-ray diffraction and electron microscopy but convenientl...

Introduction to Solid State NMR